Nitric oxide production

Improving Nitric Oxide Production and Heart Health

Few people know about nitric oxide (NO) and all the health benefits associated with it. What cannot be stated enough is that we need this little compound to thrive at our best. Nitric oxide production plays a critical role in promoting heart health. Nitric oxide works to make our blood vessels wider and more flexible. A benefit of this is improving our blood flow. This blood flow is the start of so many other wonderful benefits associated with nitric oxide production, such as circulation improvement. Failure to build sufficient amounts of nitric oxide in the body can lead to heart disease after enough time.

What Is Nitric Oxide?

A common nickname for nitric oxide is the "miracle molecule." Nitric oxide is held in such high regard because it plays a crucial role in so many cellular processes and body processes. Some of these processes include digestion, memory, immune response, and circulation. Furthermore, nitric oxide production is so important because nitric oxide is a signaling neurotransmitter. NO is used to communicate across almost every cell in the body. How does this relate to heart health? Nitric oxide production helps protect our cardiovascular systems from aging and the damage that can occur from lifestyle choices. NO helps our heart and blood vessels stay healthy and functional.

Why Nitric Oxide Production Matters For Heart Health

The main function of nitric oxide on heart health is arterial elasticity; this is a fancy way of saying NO helps our blood vessels stay flexible as we age so that blood flow can remain optimal. NO can help ensure your red blood cells do not stick together and start to form clots and blockages. NO also supports a healthy blood pressure level. The endothelial lining of your arterial walls produce nitric oxide naturally. As long as this lining stays healthy, you won't be vulnerable to inflammation and other damaging side effects of decreased nitric oxide production.

Unfortunately, nitric oxide levels begin to drop as we get older. As a result, the older you get, the more important it is to boost your nitric oxide levels. With all this in mind, you may be wondering what you can do to optimize your nitric oxide levels to avoid any unwanted heart problems?

How To Boost Your Nitric Oxide Levels For Your Heart Health

There are several ways you can ensure you have optimal nitric oxide levels for your heart health. Here are a few tips to boost nitric oxide levels:

1. Take L-arginine

L-arginine is an amino acid used as a primary precursor for nitric oxide production. This amino acid can be found in foods such as red meat, chicken, salmon, legumes, almonds, and cheese. L-arginine is also widely available as a supplement if you have food preferences or dietary restrictions that limit the exposure you can get to L-arginine through food. You can read up more about the relationship between L-arginine and nitric oxide here.

2. Eat Nitrate-Dense Foods

Certain vegetables contain a compound called nitrates. Nitric oxide production is possible through converting nitrates. Eating foods rich in nitrates will boost and optimize your nitric oxide production. Some foods high in nitrates include:

  • Spinach
  • Arugula
  • Beetroot
  • Celery
  • Lettuce
  • Kale
  • Chard
  • Radishes
  • Turnips

This list is definitely not all the vegetables out there, but it's a good start for you to begin adding nitrates into your nutrition. Eating foods that are nitrate dense can lower blood pressure as well as improve energy and stamina levels in some people.

It is worth pointing out that the nitrates found in vegetables are okay for large consumption. Processed meats such as bacon and hot dogs commonly contain nitrates. Those nitrates are used as a preservative and have been linked to some cancers. However, the nitrates from your vegetables are safe and contain antioxidants such as vitamin C. So eat your veggies, but try to avoid excessive bacon consumption. Your nitric oxide production will be boosted for sure if you do this.

3. Consume More Antioxidants

The body naturally produces nitric oxide but uses it up quickly. Because of this, it needs to be consistently replenished to keep levels high and experience the heart health benefits. One way we can do this is by introducing more antioxidants into our diets. Antioxidants are molecules that rid the body of excess free radicals that create oxidative stress. These free radicals can break down nitric oxide molecules rapidly, so we want antioxidants to stop this.

Some foods commonly associated as antioxidant-rich are:

  • Dark chocolate
  • Pecans
  • Blueberries
  • Raspberries
  • Strawberries
  • Kale
  • Beets
  • Spinach

Types of Antioxidants

Various other fruits, nuts, seeds, and vegetables aside from the ones listed above contain antioxidants as well. Some of the most common types of antioxidants are:

  • Vitamin C: Vitamin C forms connective tissues as well as produces brain chemicals to aid in nerve cell communication and signaling.
  • Vitamin E: Vitamin E shields from free radicals which can negatively impact aging and speed up the onset of some diseases. It also helps keep the immune system strong.
  • Polyphenols: The body uses polyphenols to fight off the risk of cancers and cardiovascular disease.
  • Glutathione: The body uses glutathione as a detoxifier for cells. Glutathione is known as "the mother of all antioxidants" because it is present in almost every cell in the body. It also plays a role in various body systems and functions.

Some research supports the idea that taking nitric oxide precursors such as nitrates with antioxidants can optimize nitric oxide levels by slowing down the rate of nitric oxide breakdown. Also, most vegetables that are high in nitrates are full of antioxidants. This combination allows for improved nitric oxide production and optimal consistent levels. This consistently high level of nitric oxide is what is needed to promote heart health benefits.

4. Exercise

The whole point of exercising is to get the blood pumping right? Well, your nitric oxide production increases when you exercise. Exercise promotes blood flow, which promotes the delivery of oxygen and nutrients. Not to mention the cardiovascular benefits of working your muscles, heart, and lungs consistently. Blood pressure levels and improved endothelial health can result from more exercise.

Protecting the Endothelium

Endothelium is the cellular lining within blood vessels. These are the cells that produce nitric oxide. When they produce nitric oxide, the blood vessels stay flexible and dilated for improved blood circulation throughout the body. If nitric oxide levels become insufficient, your endothelium can become dysfunctional. This dysfunction leads to heart problems and blood pressure issues like hypertension.

When we exercise, we promote endothelium health by increasing vasodilation. Vasodilation is the widening of blood vessels via relaxation of the smooth muscles within the lining of arteries. By incorporating more aerobic exercise such as jogging and walking into your daily routine, you can improve your endothelial health and increase nitric oxide production.

5. Use Nitric Oxide Boosting Supplements

This one is an obvious choice if you can checked the other boxes above. You should always try to get nitric oxide boosters from lifestyle choices and nutrition first. If you find that all of the above still isn't enough, then it's time to look into supplements. Nitric oxide supplements do not contain nitric oxide, but they do contain the precursors the body can use to convert into nitric oxide. The most common ingredients you will find are L-arginine and L-citrulline.

Both of these are amino acids. L-arginine promotes nitric oxide via the L-arginine-NO pathway. The body naturally produces L-citrulline. As a result of this natural production, L-citrulline gets converted into L-arginine. This allows for more L-arginine available for nitric oxide production. Both amino acids are great for decreasing blood pressure, so are both great for heart health. These amino acids are usually split into some ratio in a NO booster. The ideal ratio of L-arginine to L-citrulline is 2:1, which you can learn more about why here.

The Takeaway

Nitric oxide is essential for overall heart health. As vasodilation occurs, blood flow becomes more efficient. This allows more oxygen and nutrients to be available for cells and muscles. Because of this, it is important to achieve and sustain optimal nitric oxide levels.

Nitric oxide is a valuable tool to have in your health arsenal. Almost every cell in your body utilizes it. Your muscles use it for energy, stamina, and fatigue control. The brain uses it to communicate between neurons. Your blood cells use it to avoid clotting. The reproductive organs use it to increase libido and sexual health. Our immune system uses it to stay strong and vigilant against foreign intruders.

Nitric oxide is easy to add to your diet in various forms. There is no shortage of benefits to your body as a whole when supplementing nitric oxide. As a bonus, when we increase our nitric oxide consumption, our bodies begin to produce more nitric oxide naturally. If you care about living a long life with a strong heart, seriously look into what nitric oxide can do for you. If you are on any medication, talk to your doctor. Otherwise, follow the steps above and enhance your nitric oxide production asap!


Nitric Oxide Benefits

10 Nitric Oxide Benefits You Need To Know

What is Nitric Oxide?

Nitric oxide is a signaling molecule that is produced by almost every cell in the body. Nitric oxide is also a neurotransmitter, working as a signaling molecule that plays a vital role in multiple processes throughout the body. Some of these processes include digestion, blood flow, vision, memory, immune system function, recovery, etc. Nitric oxide works by relaxing and widening the blood vessels. As this happens, hormones such as growth hormone (GH) and insulin are released. Furthermore, this widening of the blood vessels is the precursor to the majority of nitric oxide benefits. This process is referred to as vasodilation. To read more about what nitric oxide is in detail, you can click here.

What is vasodilation?

Vasodilation is the relaxing and widening of blood vessels. The smooth muscles in the arterial walls relax, which allows the blood vessels to widen. As a result, blood flow improves and blood pressure lowers.

How do we make nitric oxide?

Nitric oxide is not something we produce on its own. Nitric oxide needs precursors to be produced. Primarily, these precursors are L-arginine and L-citrulline. L-citrulline will be used to produce more L-arginine and L-arginine is used to synthesize nitric oxide. Once nitric oxide is produced, we can enjoy the various health benefits. Due to all the nitric oxide benefits we can potentially experience, it is often referred to as the "miracle molecule."

Without further ado, here is a list of 10 nitric oxide benefits.

Nitric Oxide Benefits

1. Can Help Control Type 2 Diabetes

It may be a little known fact, but there is evidence showing that nitric oxide production is impaired in those suffering from type 2 diabetes. As a result of this impairment, potential problems include high blood pressure, kidney issues, heart problems, and more. Because nitric oxide is so critical for so many body and cellular processes, supplementing nitric oxide or getting more nitric oxide through diet and lifestyle choices is essential for fighting diabetes symptoms. Some of the nitric oxide benefits pertaining to diabetes include improved blood circulation, improved oxygen and nutrient delivery, improved wound healing, increased insulin sensitivity, and improved blood sugar control. The precursor of nitric oxide, L-arginine, has been suggested to be able to delay the onset of diabetes, but more research is needed before L-arginine can be looked at as a prescription for diabetics.

2. Circulation

Honestly, this nitric oxide benefit should have been first on the list. Improved blood circulation is responsible for many of the other benefits associated with nitric oxide. Since nitric oxide causes the blood vessels to widen, it makes sense that your blood circulation would improve since more blood is now flowing through the wider vessels. As blood circulation increases, nutrient and oxygen delivery improve as well. As another benefit of improved circulation, you may experience improved cardiovascular health but we will touch more on that later.

3. Sexual Health In Men

Fellas, this ones for you. If you have any issues getting your flagpole to full mass, nitric oxide may be able to help. Another nitric oxide benefit is its potential to help men suffering from erectile dysfunction (ED). Because nitric oxide improves blood flow throughout the body, it is possible that as blood delivers oxygen and nutrients more efficiently, you can experience a decrease in ED symptoms. Furthermore, nitric oxide is necessary for the penis to become erect. Contrary to what you would think, muscles around the penis have to relax in order to allow blood to flow in and give you an erection. Nitric oxide is good at relaxing smooth muscles in arterial walls. This in turn allows blood to flow in and can increase the frequency and duration of erections in men suffering from ED.

4. Blood Pressure

We kind of already touched on this nitric oxide benefit. However, in case you missed it, we can highlight the benefit here. As vasodilation allows more blood to flow through blood vessels, this decreases blood pressure. High blood pressure occurs when the force of your blood against the vessel walls is too high. Over time, high blood pressure can lead to issues such as kidney and heart disease. We want to avoid high blood pressure, so if you have hypertension or heart issues now, supplementing nitric oxide boosters may be beneficial for you in the long run.

5. Exercise Performance

This nitric oxide benefit could really help the gym bros and chicks out there. Since nitric oxide is so critical to so many processes within the body, some of those processes affect exercise performance. One of those is blood circulation. As blood circulation allows improved nutrient and oxygen delivery, muscles get more necessary fuel during and after a workout. It is because of this that many pre-workouts on the market include nitric oxide precursors such as L-citrulline and L-arginine. The takeaway here is that supplementing nitric oxide can potentially improve your energy and stamina while you work out. This will allow you to work out longer and harder, as well as recover faster.

6. Immune System Support

If you are prone to getting sick more than others around you, this nitric oxide benefit is for you. In light of the recent pandemic and the threat of future pandemics, immune system health has been a focal point for many the past few years. We all want to give our immune systems the best chance of fighting out illness. Yes, we can get vaccinated, quarantine, and all these other reactive measures. However, we can also implement some preventative measures as well.
These include a healthy diet, staying in good shape, getting quality sleep, etc. If you are already doing these, the next thing you can do is add some nitric oxide to your diet. Research suggests increasing your NO levels can improve immune system function. This is because NO is used by immune system cells to fight tumors, infections, and foreign intruders. It also sends signals throughout the body, making it crucial for getting cells prepared to fight off infections and diseases.

7. Cardiovascular and Heart Health

The nitric oxide benefits for your ticker are well worth mentioning. Due to NO's ability to kickstart vasodilation, blood pressure gets lowered. When this happens, arterial stiffness decreases and so does the risk of heart disease. Also, improved blood flow allows the heart to pump blood more efficiently, helping the heart stay strong and healthy thanks to the optimal oxygen and nutrient delivery.

8. Wound Healing

This nitric oxide benefit is a little nuanced because other factors are at play when it comes to your ability to heal from a wound. However, it is hypothesized that because NO is a signaling molecule and is a key component of immune system function it has a role in wound healing. NO is likely partially responsible for skin rebuilding after an injury since it would signal immune system cells and repair cells to do their jobs. More research is needed to determine the extent of the role nitric oxide plays in wound healing.

9. Reproduction Health

This nitric oxide benefit applies to men and women. For women, nitric oxide plays a role in menstrual regulation, pregnancy progression, and fetal development from embryo to newborn during the duration of the pregnancy term. There is research suggesting potential fetal development can be impaired if there are insufficient NO levels in the mother's body.

For men, NO helps regulate sperm development, sperm motility, sperm strength (ability to penetrate an egg), and sperm maturity. Insufficient NO levels can lead to low sperm count and low sperm vitality. Also, since nitric oxide helps with ED, nitric oxide helps sperm get delivered via improved erections.

10. Brain Health

If you or your family have a history of neurodegenerative disorders, this will likely pertain to you. Turns out that supplementing nitric oxide can improve blood flow to the brain. Furthermore, since nitric oxide is a signaling neurotransmitter, it plays an important role in intracellular communication between neurons in the brain. Because of the role NO plays in neuron communications, NO can potentially aid in the treatment of diseases like dementia and Alzheimer's.

Other Reported Nitric Oxide Benefits

There are already plenty of reasons to look into increasing NO consumption. However, people often take NO supplements for reasons other than well-researched benefits. Some possible benefits which are strictly anecdotal are:

improved lung function for those with lung-debilitating illnesses

preventing COVID-19

improving memory loss

preventing common colds

treating altitude sickness

speeding up weight loss

healing foot ulcers

speeding up recovery after a major injury

speeding up recovery after a major trauma

Other Nitric Oxide Benefits

Many of the benefits have some scientific research backing them up, but not enough to be a routine prescription from doctors. Most of the time, you can easily add more nitric oxide into your life by:

eating foods high in nitrate

eating foods high in antioxidants

increasing sunlight exposure

decreasing stress

nose breathing

limiting mouthwash use

exercise

The Takeaway

This list is far from exhaustive, but it's a good start for increasing NO levels. There are very few side effects for you to worry about, so NO is safe for most people to consume. If you have any blood pressure or heart medications, certainly ask your doctor for advice before trying to actively increase your nitric oxide levels. Always ensure you are safe before adding anything to your health regimen. Nitric oxide plays a role in so many processes related to human health. If it makes sense for you to add more in or supplement with an NO booster, do so. If you are not sure where to look, click here.


L-citrulline: everything you need to know

L-Citrulline: Everything You Need To know

What if I told you there is a supplement out there in the vast wild west known as the health industry that can improve cognitive health, improve exercise performance, improve blood flow, and more? Would you be interested in learning about this supplement? If so, you've come to the right place. L-citrulline has been gaining popularity in fitness circles recently for its possible benefit of improving exercise performance. If you're reading this, chances are you care about more than your post-workout pump. L-citrulline has a host of other potential benefits as well as risks. We will explore the ins and outs of L-citrulline so you have all the facts. Let's go over everything you could ever need to know about this supplement and see if it's worth adding to your health and wellness protocols.

What Is L-Citrulline?

L-citrulline is an amino acid that occurs naturally in the body. Foods such as watermelon and pumpkin seeds contain high levels of L-citrulline. Since the body produces L-citrulline naturally, we call it a nonessential amino acid. Even though L-citrulline is an amino acid, it does not directly impact protein synthesis. However, it still has value in other processes within the body. L-citrulline could also potentially increase chemicals in the body that aid in protein synthesis. One such chemical process L-citrulline is a vital component of is the urea cycle. This cycle is responsible for flushing harmful compounds such as ammonia from the body. Urine flushes out the urea that remains. So now you know what L-citrulline is, let's look at how it works.

How Does L-Citrulline Work?

We know that L-citrulline is an amino acid produced in the body and used for various body processes. One of those processes is vasodilation. Vasodilation is the relaxing and widening of blood vessels. This process is made possible via the conversion of L-citrulline into another amino acid, L-arginine. When this happens, L-arginine gets converted into nitric oxide. This in turn promotes vasodilation thanks to the relaxing of cells within the blood vessels. A popular question amongst nutrition experts is: "why should we supplement L-citrulline for vasodilation when it's converted into L-arginine anyway?" Why not just supplement L-arginine?

This is a fair question, and maybe one you are asking as well. What researchers found is the body seems to better absorb L-citrulline, or at least differences in absorption rate demonstrate consuming L-citrulline may increase the bioavailability of L-arginine better than consuming L-arginine itself. We have already touched on a couple benefits of L-citrulline, but let's dive a little deeper now.

What are the benefits of L-Citrulline?

L-citrulline has had research conducted to look into the potential benefits for various areas of health. This includes cognition, sexual health, exercise performance, fatigue recovery, blood flow, etc. Let's dive into the benefits of L-citrulline so you can see why it may be smart o add it to your supplement stack.

Improved Blood Flow

The first benefit is the most obvious benefit, and the benefit discussed most often. L-citrulline may improve the expansion of blood vessels via vasodilation. This vasodilation can make blood flow more efficiently throughout the body. As a result of this more efficient blood flow, delivery of oxygen and nutrients to the muscles and other cells of the body also improves. As the delivery of nutrients and oxygen improves, so does the removal of waste materials in those muscles and cells. as a final note, it is worth stating that a single dose is unlikely to yield any significant results, so continual supplementation has a far greater likelihood of benefit. This is especially true if you have any underlying heart health issues.

Reduced Blood Pressure

If you have any hypertension issues, L-citrulline may come in handy. There is some research showing L--citrulline may help lower blood pressure, especially if you have high blood pressure. There is less research supporting improved blood pressure for already healthy individuals, but rest assured there are other benefits for you.

Better Pump

A side benefit to better blood flow is the improved delivery of oxygen and nutrients to cells of the body; this includes muscle cells. When blood flows faster into muscles, this creates a fuller and thicker appearance. Bodybuilders call this thicker and fuller appearance the "pump." The pump creates a full and defined physical appearance, which is the ideal look competitive bodybuilders chase for stage competitions as well as photoshoots. If you are trying to achieve this particular look, supplementing L-citrulline might be useful.

Increase of GH Production

For those of you looking to add some muscle mass to your physique, L-citrulline might have another benefit for you. There is some research that suggests supplementing L-citrulline (particularly citrulline malate) can promote growth hormone production during and after your workout. As growth hormone production increases, your recovery time improves and you are likely to see muscle growth faster. There are plenty of other factors that do more for growth hormone production, but supplementing L-citrulline can certainly be complementary to other factors such as improving sleep quality, reducing sugar intake, eating more protein, etc.

Increased Energy Levels and Improved Exercise Performance

We all want to be able show to every workout with high energy and crush it with crazy intensity. I'm sure most of you would also love to have enough energy everyday to not need the morning cup(s) of coffee and/or a 3pm nap just to function like a human most days. Lucky for you, L-citrulline might be able to help. Some consumers of L-citrulline have reported increased energy levels, which is why L-citrulline is a common ingredient in pre-workout mixes. Supplementing L-citrulline increases production of ATP (adenosine triphosphate), which is likely a major contributor to this benefit. Increasing ATP leads to an increase in energy and improved fatigue resistance.

L-citrulline research has looked at multiple styles of exercise to establish exercise performance benefits. Researchers have looked at High Intensity Interval Training (HIIT), Endurance Training, and General Strength Training to see the effects of L-citrulline. A variation of L-citrulline called citrulline malate has been studied alongside L-citrulline. The only difference you need to know is that citrulline malate contains malic acid, which can improve absorption rate and bioavailability of L-citrulline in the body. This of course improves energy levels by making more energy available to be used.

To briefly sum up the gist of the research, L-citrulline seems to be more useful for endurance training while citrulline malate seems to be more useful for strength training and HIIT training. Regardless of which variation of citrulline you choose to supplement, they will likely give you more energy to push yourself harder during the workout and recover faster after the workout.

Improved Brain Function

We have established that L-citrulline not only aids in vasodilation (widening of blood vessels, but is a precursor to nitric oxide (NO), a molecule responsible in part for intracellular signaling. This intracellular signaling includes the neurons in the brain. Put these two things together, and you see the importance of L-citrulline for brain health. L-citrulline can improve the delivery of oxygen, blood, and nutrients to the brain the same as it does to other areas of the body. Potential side effects of this are sharper focus, feeling more alert, and improved mood.

Improved Sexual Health

This potential benefit varies amongst studies and is inconclusive, but there is some research showing a decrease in mild erectile dysfunction symptoms. There is also some potential improvement in the ability to maintain an erection. This is likely due to the increased blood flow via vasodilation from the L-citrulline being converted into nitric oxide.

Taking L-Citrulline

Different studies will tell you different amounts, but a generally accepted amount of L-citrulline (for blood pressure and/or endurance training) would be 3-6 grams daily. Some research that suggests if you take citrulline malate (strength training/HIIT) instead, a slightly higher dosage of up to 8-10 grams a day could be beneficial. There is little feedback from consumers of side effects such as upset stomach, so taking 8-10 grams a day should not warrant any negative effects. There is also little to no reported benefit to exceeding 10 grams per day.

Side Effects and Safety Concerns

Preliminary research has been conducted in regard to excessive L-citrulline consumption. Thankfully there seems to be no reported negative side effects of consuming up to 15 grams per day routinely. There are no reported benefits to exceeding the 8-10 grams per day recommendation either. No research has shown any negative impacts on body function or blood pressure. Furthermore, there is evidence that exceeding 10 grams per day likely leads to the body flushing the excess L-citrulline, so it appears to be a waste of time and money to exceed 10 grams per day.

The Crux Of The Matter

Here's the bottom line: L-citrulline is an amino acid with an array of health benefits. This amino acid can provide energy to crush the toughest workouts, improves blood flow, helps promote nitric oxide, improves brain health, and more! You have plenty to gain and almost nothing to lose by adding L-citrulline to your supplement stack. If you want to improve heart health and be able to train harder, L-citrulline is a solid bet. Like I previously stated, many pre-workout mixes contain L-citrulline, so you are unlikely to need to supplement it by itself. However, if you're looking for a product that contains not only L-citrulline, but L-arginine as well, be sure to check out the Bionox M3 line!


nitric oxide boosting foods

Nitric Oxide Boosting Foods You Should Be Eating

Have you never heard of nitric oxide? If not, you might want to take the time to familiarize yourself with this powerful and chemical. This miracle molecule has so many benefits for your body and overall health; it cannot be covered in a single article.
Nitric Oxide (NO) is a molecule produced naturally in the body which is vital to numerous aspects of health. Nitric oxide does most of its work via vasodilation, relaxing and widening the blood vessels. This process is where the magic happens, allowing for improved blood flow and a wide range of health benefits as a by-product. One of the best ways to naturally increase NO production in the body is simply making changes to your diet.
There are a LOT of nitric oxide boosting foods out there that can enhance nitric oxide production, so it will be impossible to list them all without making this way too long to read. I will break down some of the most popular foods used to enhance nitric oxide production to make the list more concise. So here is a list of foods you can start eating today to boost your nitric oxide levels.

1. Beets

This one should come as no surprise to anyone who knows anything about nitric oxide. This powerhouse of a superfood is essential for anyone looking to maximize nitric oxide levels purely through diet. Beets are a vegetable highly rich in dietary nitrates, which your body can use to convert into nitric oxide. This root has been linked to multiple health benefits such as improved cognitive function, boosting stamina, improving blood flow, and lowering blood pressure. Beets are a great choice for decreasing the risk of heart issues as you age, so consider supplementing them if you like to eat your red foods.

2. Garlic

If you aren’t a vampire, this one will work well for you. Garlic can enhance nitric oxide production by activating an enzyme called nitric oxide synthase. This enzyme helps the amino acid L-Arginine convert into nitric oxide. Garlic has been linked to improved exercise tolerance and decreased blood pressure so if you like eating garlic, you’re in luck.

3. Pomegranates

Within some circles of the fitness community, this one is a useful hack. Pomegranate juice has been used by bodybuilders for years to decrease muscle soreness and improve recovery between training sessions. Pomegranates can do much more though. Pomegranates are high in polyphenol antioxidants as well as nitrates, making them excellent vasodilators. This vasodilation promotes blood flow as well as potentially improved oxygen and nutrient delivery to cells, hence the usefulness for active individuals.
Even if you are not super active, the antioxidants found in pomegranates are great for protecting your cells from oxidative damage. Furthermore, the increased blood flow from vasodilation can potentially improve conditions such as erectile dysfunction and hypertension. If you’re a fan of sweet fruit juices, add pomegranates as a nitric oxide boosting food.

4. Eggs

Eggs are a go-to for many people as a breakfast staple food. This one is also another staple for fitness buffs who want to make sure they get their morning protein fix. There may be something to the eggs for breakfast we are all ingrained with from an early age. Eggs happen to be high in the amino acid L-Arginine, a precursor to nitric oxide. L-Arginine helps release nitric oxide into the blood, which in turn channels all the wonderful benefits of nitric oxide such as improved blood circulation, endothelial function, etc.

While the body does produce L-Arginine naturally, as we age this production may not be enough to provide the body what it needs to function optimally. For this reason, finding foods high in amino acids like L-Arginine is crucial for staying active and healthy as we age. Eggs are easily accessible for most people, so it’s an easy choice for a nitric oxide boosting food (provided you are not a vegetarian).

5. Watermelon

As we move into the summer season, watermelon is a classic fruit choice for hydrating and enjoying a sweet and healthy treat. Like most things on this list, watermelon has many other uses outside of being delicious. Watermelon is known for having high levels of the amino acid L-citrulline, another precursor amino acid to produce nitric oxide. The body uses L-Citrulline to create L-Arginine, which in turn facilitates the production of nitric oxide. As you may know by now, this NO production thanks to the conversion of L-Citrulline into L-Arginine allows blood vessels to relax and widen, improving blood circulation as well as a host of other health benefits. Whether this treat is a sweet snack or an intentional diet choice, you cannot go wrong with this nitric oxide boosting food.

6. Pumpkin Seeds

Who else is a BIG FAN of Halloween? What is one item that jumps out at you when you think of Halloween? Is it the candy? The costumes? The slight chill in the air? If you’re like me, you think of jack-o-lanterns and all the cool carvings you can do. I go on Pinterest every year and try to replicate (often to comical failure) an extravagant pumpkin carving. Pumpkins can serve another purpose; one more healthy and possibly less frustrating than trying to copy the cool Pinterest carving. No, I do not mean pumpkin pie (but that is good).

Pumpkins can boost your nitric oxide levels! Pumpkin seeds contain antioxidants that work to rid the body of excess free radicals as well as improve blood flow. This improved blood flow reduces the risk of plague buildup in blood vessels and reduces the risk of hypertension and other heart health problems. So, this Halloween when you go to scrape out your pumpkin to carve a ghoulish jack-o-lantern, keep the seeds. Those seeds are a nitric oxide boosting food you don’t want to waste!

7. Cucumber

Where are my salad peeps at? This one is for you. If you are a fan of salads, chances are you eat cucumber. Pickle fans will also fall into this one to some degree. Cucumbers have decent amounts of the amino acid L-Citrulline, so the body will convert the L-Citrulline into L-Arginine for nitric oxide to be produced and released. Cucumbers do not have as much L-Citrulline as watermelon, but they are lower in sugar and calories. Like watermelon, cucumbers are mostly water, so are naturally hydrating as well. If you’re looking for a nitric oxide boosting food that is low in sugar and low in calories, cucumber is a must-add to your diet.

8. Spinach

Who remembers the jingle Popeye the Sailor Man used to sing when he would prepare to accomplish superhuman feats of strength to save Olive Oyl? If you were a fan of the cartoon, you know Popeye charged up by gobbling down a big tin can full of spinach. Ironically, despite the hyperbole there is something to Popeye being charged up on this leafy green.

Spinach is one of those vegetables like beets with high levels of natural nitrates. These nitrates convert directly into nitric oxide. Because of these dietary nitrates, spinach is a great addition to your diet. On top of this, regular consumption of spinach and other leafy greens like arugula can reduce the risk of cognitive function decline and cardiovascular issues. Maintaining optimal levels of nitric oxide has been linked to boosted energy levels and improved stamina in people, so Popeye had the right idea. Be like Popeye the Sailor Man and add this nitric oxide boosting food to your diet.

9. Beef and Fish

Red meat and seafood are not the same thing. However, in terms of nitric oxide boosting these foods act in similar ways so I will discuss them together. Meats such as beef and fish both contain high levels of Coenzyme Q10 (CoQ10). CoQ10 helps preserve the nitric oxide levels in your body. Almost every cell in your body contains CoQ10. This compound is vital to processes such as energy promotion and ridding the body of free radicals. Having ample CoQ10 also promotes good heart health, so it’s a good idea to have it in your diet anyway. Animal foods such as seafood and red meat have some of the highest amounts of CoQ10 available naturally. Since CoQ10 has been linked to being able to preserve nitric oxide within the body, it is certainly a nitric oxide boosting food to add if dietary preferences allow.

10. Chocolate

As how most people do with eating, we saved the dessert for last. The last food I’m including on this list is chocolate, specifically dark chocolate. Dark chocolate is not for everyone since it is typically less sweet than milk or white chocolate. However, dark chocolate has a few health benefits if consumed reasonably. Dark chocolate contains compounds called flavanols due to the cocoa concentrations in dark chocolate. These compounds rid the body of free radicals as well as increase nitric oxide levels in the body. Dark chocolate has been shown to lower stress, reduce blood pressure, and improve brain function in some studies. Most studies advise consuming dark chocolate with a 70%-80% cocoa concentration. While it isn't as sweet of a dessert as you might like, it’s still cool chocolate is a nitric oxide boosting food.

Eat Well. Live Well.

This list is far from exhaustive. Other foods you can add to your diet include arugula, broccoli, citrus fruits, other seeds and nuts, poultry, kiwi, kale, cabbage, Bok choy, spirulina, red wine, and so many more. Chances are you can find something out there that will fit your dietary preferences and restrictions that will boost your nitric oxide levels while tasting great!


Bionox is the Proud Sponsor of SOHO Expo 2021

Dr. Jay Wilkins and Professional Golfer Chris DiMarco, having a blast doing what they love.

The SOHO EXPO is a Natural Products Industry Trade Show and Convention. The convention offers a perfect mix of natural products industry along with speakers ranging from professors, doctors, health food store owners, and more. Our founder and formulator, Dr. Jay Wilkins, even had the opportunity to present on Nitric Oxide: Your Body's Best Medicine.

Bionox had the honor of sponsoring the SENPA Expo 2021. It was a pleasure to see everyone's smiling faces in person in sunny Orlando, Florida. We even had professional golfer, Chris DiMarco, come out and host a training session for the lucky guests that we able to join!

Dr. Jay Wilkins giving his presentation on Nitric Oxide: Your Body's Best Medicine

"It was wonderful to see everyone out and about. I enjoyed getting on the golf course with the golf legend, Chris DiMarco. I know the fans enjoyed it as well. Overall it was a great weekend filled with golf and learning. We had numerous people come to our booth to learn about the miracle molecule, nitric oxide, and to putt a few holes!" -Dr. Jay Wilkins

PGA Golf Legend, Chris DiMarco, showing us how it's done!

If we missed you this year, make sure you are subscribed to our email newsletters so you can come next year. We have multiple opportunities to come out and have some fun. We hope to see your smiling faces soon! For now check us out at www.bionoxusa.com.


Positively Natural Marketplace

The annual Positively Natural Marketplace event is the premier natural product trade show and educational conference in the Western Region. Made for private, wholesale buyer show only.

Dr. Jay giving his presentation at Positively Natural Marketplace Event

On October 21st and 22nd, Bionox had the privilege to sponsor the event. Our founder and formulator, Dr. Jay Wilkins was able to share our story with others and enlighten them on the 'miracle molecule,' nitric oxide!

Dr. Jay Wilkins giving the Nitric Oxide: Your Body's Best Medicine Presentation

Nitric oxide is produced by almost every cell in the body, and one of the most important molecules for blood vessel health. At Bionox we use the l-arginine method found in M3 Ultimate Nitric Oxide Nutrition, and the nitrate method found in Nox3 Greens and Nox3 Beets. In Dr. Jay's presentation, he goes in to the detail regarding the benefits and future of nitric oxide.
A few benefits include:

  • Circulation
  • Muscle and Bone Recovery
  • Athletics
  • Vitality
  • Vision
  • Brain Function
  • Cellular Energy
  • Digestion

Learn more about the arginine pathway here.

Learn more about the nitrate pathway here.

Dr. Jay Wilkins and friends with at the Bionox booth.

Shop all Bionox products here.

Facebook @Bionox

Twitter @BioNoxNutrients

Instagram @bionoxusa


Bionox Nutritional Supplement Provides a Natural Boost of Nitric Oxide for Sports Performance, Endurance and Recovery

Athletes across all levels and disciplines often seek natural ways to improve performance, endurance, and recovery time. A 2020 meta-analysis conducted on 18 studies of arginine supplementation found that this amino acid can improve performance in anaerobic, aerobic, and high intensity activities.1 Further studies have shown that arginine supplementation can also support faster recovery, an important consideration for athletes.2 Arginine is an amino acid produced naturally by the body that can also be supplemented for various functions, including athletic performance. Bionox has been working with arginine and similar molecules to motivate wellness in athletes and fitness enthusiasts since 2005.

One reason that arginine supplements support performance is that they are a natural precursor to nitric oxide production. Nitric oxide is a molecule created by the body that supports vasodilation and therefore blood and oxygen flow. Nitric oxide supports cardiovascular, muscle and respiratory health, making it an essential focus for the athlete or athletically inclined. In 2005 after the revolutionary 1998 Nobel Prize winning research on nitric oxide crossed Dr. Jay Wilkins’s desk, he dedicated his life to improving lives through nitric oxide nutrition through his company Bionox.

Nitric oxide has been researched in over 14,000 articles since 1980, confirming that, as Dr. Wilkins says, “absolutely everything in the body depends on it.” It was with this in mind that Bionox created their scientifically formulated supplements. Bionox’s signature product M3 Ultimate Nitric Oxide Nutrition is a potent combination of nutrients that activate the innate power of the body to increase nitric oxide production.

The formula features arginine, but also includes additional nitric oxide precursors such as l-citrulline, beet root powder, and watermelon extract. This unique blend makes for an effective three stage nitric oxide supplement that supports health and athletic performance. M3 Ultimate Nitric Oxide Nutrition also includes natural ingredients, such as hawthorne berry, horse chestnut, amla, green coffee bean, camu camu, grape seed and skin, pomegranate and other vitamins and minerals that support successful nitric oxide production. M3 Ultimate Nitric Oxide Nutrition is trusted by doctors globally, is vegetarian, gluten-free, soy-free, vegan, made in the USA, sugar-free and non-GMO.

Athletes and coaches love M3 Ultimate Nitric Oxide Nutrition:

“Sports and fitness have always been a huge part of my life. I was a wide receiver for the San Jose State Spartans up until 2013. The last 9 years have been dedicated to training some of the fastest athletes ever to run the 100 meter and 60 meter dash in the US history. I have coached national record holders, multiple state champions, and national champions in Team USA track and field.

I love using Bionox M3 Ultimate Nitric Oxide Nutrition for all my athletes. M3 gives them an advantage in recovery and performance. My athletes over the years have consistently seen tremendous results in endurance, strength gains in the weight room, and better recovery when taking the formula. I have noticed a big difference in our championship victories as it helps my athletes get a competitive edge on the track. My recommendation for them is to take 2 scoops an hour before track practice and additional scoop before sleep for added recovery during heavy training cycles. M3 gets it done!” - Joshua Harrison, former wide receiver San Jose State Spartans

M3 Ultimate Nitric Oxide Nutrition can be purchased in 30 or 60 scoop containers in Original Berry Flavor or Citrus Flavor with Vitamin K2. Individual packets are also available on bionoxusa.com/ or on amazon.com.

About Bionox

Bionox® was founded by Dr. Jay Wilkins, a naturopathic doctor who has been in the health and wellness industry for over 25 years. As a health practitioner, Dr. Jay Wilkins was interested in the science of nutrition and supplementation. When discovering the effectiveness of nitric oxide to maximize health in the body, Dr. Jay Wilkins researched and developed Bionox’s first product, as their flagship product - M3 Ultimate Nitric Oxide Nutrition. M3 provides a potent combination of nutrients that activates the innate power of the body to realize optimum health. Bionox mission is to motivate all to unlock their own wellness through providing trusted solutions to overcome life’s challenges and live life fully. Their potent formulas for nitric oxide nutrition, Bionox M3 comes in both Citrus Flavor and Original Berry Flavor, available as a one-month supply, 15-day supply, and stick packs. Bionox has developed other blends for motivating wellness with their Ultimate Sugar Balance Support, Chelanox, M-Mune3, and Nox3 Daily Greens. Bionox is motivating all to live life, fully.

Media Contact

For more information about Bionox please visit bionoxusa.com/. For media inquiries, requests for product samples, high-res images, or to set up an interview with Bionox Nutrients founder Dr. Jay Wilkins, please contact Halle Barnett, [email protected] or at 678-756-8282.


Nitric Oxide Supplements Can Support Millions of Americans Suffering from Diabetes

According to the CDC approximately 34.2 million adults had diabetes and 88 million adults had prediabetes in 2018 in the United States alone. 1 Diabetes is a serious chronic disease that causes many unwanted symptoms such as weight gain, liver, kidney, pancreas and digestive issues, cardiovascular disease, brain fog, memory loss, numbness and more. The challenges of maintaining healthy blood sugar equilibrium can be especially challenging during the holidays and winter. “People who have diabetes are not producing enough nitric oxide,” states Dr. Jay Wilkins, founder of Bionox. Supporting the body’s nitric oxide production, Bionox provides SB3 Ultimate Sugar Balance Support to stabilize blood sugar and M3 Ultimate Nitric Oxide Nutrition to support waning nitric oxide levels to realize optimum health.“ When it comes to blood sugar supporting supplements,” says Dr. Wilkins, “The three main issues to address
are: support the pancreas and its’ ability to make insulin, support the ability for insulin to get into the cells, and support lost nitric oxide levels to deter damage to the arteries, kidneys, and other critical health concerns associated with diabetes.”

Bionox created SB3 Ultimate Blood Sugar Support alongside nitric oxide nutrition with 20 carefully selected ingredients to assist the liver and pancreas to stabilize blood sugar equilibrium. SB3 stabilizes blood sugar by stimulating glucose uptake and its oxidation in cells, reducing insulin resistance and improving insulin sensitivity, helping cells fight against oxidative stress, activating insulin signaling pathways, and supporting glucose uptake by cells and clearance of glucose from the blood. SB3 active ingredients include: vanadyl sulfate, cinnamon, gymnema sylvestre, biotin, bitter melon, magnesium, banaba leaf, zinc, manganese, L-taurine, vitamin C, vitamin E, and alpha lipoic acid. SB3 formula has the most researched vitamins, minerals, amino acids, and herbs to maintain the body’s delicate sugar equilibrium. SB3 is vegetarian, gluten-free, soy-free, made in the USA, vegan, sugar-free and non-GMO.

diabetic supplements nitric oxide

Bionox M3 Ultimate Nitric Oxide Nutrition is an excellent adjunct to SB3 to support waning nitric oxide levels
for people with blood sugar issues. M3 provides a 24-hour release of nitric oxide production in the body, reducing the risk of health complications from blood sugar imbalance. Nitric oxide helps the tissue to become more sensitive to insulin, and arginine is a precursor to insulin. Both arginine and citrulline are amino acids that convert into nitric oxide. In M3, Bionox utilizes the right amounts and ratio of arginine and citrulline, including beet root powder and watermelon, and combines potent antioxidants from vitamins C, D, E, and other botanicals and minerals to help boost and sustain nitric oxide in the body. For instance, by adding a proprietary blend of AstraGin® increases absorption of nitric oxide up to 60%, and by adding antioxidants, Vitamin C, D and E, and other botanicals, to protect the nitric oxide from damaging free radicals.

According the CDC, diabetes and heart health go hand in hand. 2 Nitric oxide reduces the risks of health complications with blood sugar issues as it
supports the cardiovascular system by widening blood vessels, lowering blood pressure, and improving circulation. “One diabetic specialist used to send 250 patients a year to cardiologists,” says Dr. Jay Wilkins, “Since using L- arginine, L-citrulline, antioxidants and vitamin D with his patients he sends maybe one per year. He has been using nitric oxide supporting supplements like M3 Ultimate Nitric Oxide Nutrition with his diabetic patients for over 20 years.”
Don’t just take Dr. Wilkins’ word for it, hundreds of customers have given both M3 Ultimate Nitric Oxide Nutrition and SB3 Ultimate Blood Sugar Support raving reviews.

3 Months and you will not live without this product again!
WE LOVE M3!!! My father used to sit around in sweaters and blankets, but after 2-3 months on M3 he never
again complained about being cold, and my diabetic husband got the same results! His blood sugar has come
down so much and he has decided to stop taking his medication on his own because the benefits he's gotten
with M3 were more effective than the insulin which also made him dizzy. I'm pleased that this is a doctor
recommend formula that has integrity - what's on the label is truly in the product! I have a Health & Wellness
shop and now can recommend M3 to my clients who are themselves enjoying their own wonderful experiences
- including great sleep as well. I highly recommend taking M3 for at least 3 months to see how well it will help
you or your loved ones without delay. Thanks Bionox for a top notch nitric oxide product!!
- D. Weaver

It works, I love it.
Love it. I've been taking this now for a little over a week and it makes a huge difference. I usually get the shakes
around 2pm and am told by my doctor that my blood sugar level were low that's why this was happening. To
curb the shakes I would go for the unhealthy sugary snacks. This has helped with that and I no longer reach for
the candy. This product works as intended. Would highly recommend.
- Jae

It works.
I used the product to reduce my pre-diabetes. I did a follow up with my doctor after using it for a while and my
blood sugar was normal.
- Happy Customer

Ultimate Nitric Oxide Nutrition and Ultimate Blood Sugar Support can be purchased on bionoxusa.com or at Amazon.

About Bionox
Bionox® was founded by Dr. Jay Wilkins, a naturopathic doctor who has been in the health and wellness industry for over 25 years. As a health practitioner, Dr. Jay Wilkins was interested in the science of nutrition and supplementation. When discovering the effectiveness of nitric oxide to maximize health in the body, Dr. Jay Wilkins researched and developed Bionox’s first product, as their flagship product - M3. M3 provides a potent combination of nutrients that activates the innate power of the body to realize optimum health. Bionox mission is to motivate all to unlock their own wellness through providing trusted solutions to overcome life’s challenges and live life fully. Their potent formulas for nitric oxide nutrition, Bionox M3 comes in both Citrus Flavor with
Vitamin K2 and M3Original Berry Flavor, available as a one-month supply, 15-day supply, and stick packs. Bionox has developed other blends for motivating wellness with their Sugar Balance Botanical Blend, Chelanox, M-Mune3, and Nox3 Daily Greens Ultimate Raw Food Blend. Bionox is motivating all to live life, fully.

Media Contact
For more information about Bionox please visit bionoxusa.com. For media inquiries, requests for product
samples, high-res images, or to set up an interview with Bionox founder Dr. Jay Wilkins, please contact Halle Barnett, [email protected] or at 678-756-8282.


Nitric Oxide Nutrition Can Support Millions of Americans Suffering from Diabetes

According to the CDC approximately 34.2 million adults had diabetes and 88 million adults had prediabetes in 2018 in the United States alone. 1 Diabetes is a serious chronic disease that causes many unwanted symptoms such as weight gain, liver, kidney, pancreas and digestive issues, cardiovascular disease, brain fog, memory loss, numbness and more. The challenges of maintaining healthy blood sugar equilibrium can be especially challenging during the holidays and winter. “People who have diabetes are not producing enough nitric oxide,” states Dr. Jay Wilkins, founder of Bionox. Supporting the body’s nitric oxide production, Bionox provides SB3 Ultimate Sugar Balance Support to stabilize blood sugar and M3 Ultimate Nitric Oxide Nutrition to support waning nitric oxide levels to realize optimum health.

“When it comes to blood sugar supporting supplements,” says Dr. Wilkins, “The three main issues to address are: support the pancreas and its’ ability to make insulin, support the ability for insulin to get into the cells, and support lost nitric oxide levels to deter damage to the arteries, kidneys, and other critical health concerns associated with diabetes.”

Bionox created SB3 Ultimate Blood Sugar Support alongside nitric oxide nutrition with 20 carefully selected ingredients to assist the liver and pancreas to stabilize blood sugar equilibrium. SB3 stabilizes blood sugar by stimulating glucose uptake and its oxidation in cells, reducing insulin resistance and improving insulin sensitivity, helping cells fight against oxidative stress, activating insulin signaling pathways, and supporting glucose uptake by cells and clearance of glucose from the blood.

SB3 active ingredients include: vanadyl sulfate, cinnamon, gymnema sylvestre, biotin, bitter melon, magnesium, banaba leaf, zinc, manganese, L-taurine, vitamin C, vitamin E, and alpha lipoic acid. SB3 formula has the most researched vitamins, minerals, amino acids, and herbs to maintain the body’s delicate sugar equilibrium. SB3 is vegetarian, gluten-free, soy-free, made in the USA, vegan, sugar-free and non-GMO.

Bionox M3 Ultimate Nitric Oxide Nutritionis an excellent adjunct to SB3 to support waning nitric oxide levels for people with blood sugar issues. M3 provides a 24-hour release of nitric oxide production in the body, reducing the risk of health complications from blood sugar imbalance. Nitric oxide helps the tissue to become more sensitive to insulin, and arginine is a precursor to insulin. Both arginine and citrulline are amino acids that convert into nitric oxide. In M3, Bionox utilizes the right amounts and ratio of arginine and citrulline, including beet root powder and watermelon, and combines potent antioxidants from vitamins C, D, E, and other botanicals and minerals to help boost and sustain nitric oxide in the body. For instance, by adding a proprietary blend of AstraGin® increases absorption of nitric oxide up to 60%, and by adding antioxidants, Vitamin C, D and E, and other botanicals, to protect the nitric oxide from damaging free radicals.

According the CDC, diabetes and heart health go hand in hand. 2 Nitric oxide reduces the risks of health complications with blood sugar issues as it supports the cardiovascular system by widening blood vessels, lowering blood pressure, and improving circulation. “One diabetic specialist used to send 250 patients a year to cardiologists,” says Dr. Jay Wilkins, “Since using L- arginine, L-citrulline, antioxidants and vitamin D with his patients he sends maybe one per year. He has been using nitric oxide supporting supplements like M3 Ultimate Nitric Oxide Nutrition with his diabetic patients for over 20 years.”

Don’t just take Dr. Wilkins’ word for it, hundreds of customers have given both M3 Ultimate Nitric Oxide Nutrition and SB3 Ultimate Blood Sugar Support raving reviews.

3 Months and you will not live without this product again!

WE LOVE M3!!! My father used to sit around in sweaters and blankets, but after 2-3 months on M3 he never again complained about being cold, and my diabetic husband got the same results! His blood sugar has come down so much and he has decided to stop taking his medication on his own because the benefits he's gotten with M3 were more effective than the insulin which also made him dizzy. I'm pleased that this is a doctor recommend formula that has integrity - what's on the label is truly in the product! I have a Health & Wellness shop and now can recommend M3 to my clients who are themselves enjoying their own wonderful experiences - including great sleep as well. I highly recommend taking M3 for at least 3 months to see how well it will help you or your loved ones without delay. Thanks Bionox for a top notch nitric oxide product!!

- D. Weaver

It works, I love it. Love it.I

've been taking this now for a little over a week and it makes a huge difference. I usually get the shakes around 2pm and am told by my doctor that my blood sugar level were low that's why this was happening. To curb the shakes I would go for the unhealthy sugary snacks. This has helped with that and I no longer reach for the candy. This product works as intended. Would highly recommend.

- Jae

It works.

I used the product to reduce my pre-diabetes. I did a follow up with my doctor after using it for a while and my blood sugar was normal.

- Happy Customer

Ultimate Nitric Oxide Nutrition and Ultimate Blood Sugar Support can be purchased on bionoxusa.com or at Amazon.

About Bionox

Bionox® was founded by Dr. Jay Wilkins, a naturopathic doctor who has been in the health and wellness industry for over 25 years. As a health practitioner, Dr. Jay Wilkins was interested in the science of nutrition and supplementation. When discovering the effectiveness of nitric oxide to maximize health in the body, Dr. Jay Wilkins researched and developed Bionox’s first product, as their flagship product - M3 Ultimate Nitric Oxide Nutrition. M3 provides a potent combination of nutrients that activates the innate power of the body to realize optimum health. Bionox mission is to motivate all to unlock their own wellness through providing trusted solutions to overcome life’s challenges and live life fully. Their potent formulas for nitric oxide nutrition, Bionox M3 comes in both Citrus Flavor and Original Berry Flavor, available as a one-month supply, 15-day supply, and stick packs. Bionox has developed other blends for motivating wellness with their Ultimate Sugar Balance Support, Chelanox, M-Mune3, and Nox3 Daily Greens. Bionox is motivating all to live life, fully.

Media Contact

For more information about Bionox please visit bionoxusa.com. For media inquiries, requests for product samples, high-res images, or to set up an interview with Bionox founder Dr. Jay Wilkins, please contact Halle Barnett, [email protected] or at 678-756-8282


People, Now More Than Ever, Are Focused on Keeping Their Immune System Strong

https://cdn.shopify.com/s/files/1/2128/1645/files/October_Press_Release_-_People_are_focused_on_keeping_their_immune_system_strong.pdf?v=1610555802

According to the Center for Disease Control and Prevention, people with weakened immune systems are at a higher risk of getting severely sick from COVID. Strengthening the immune system, as during the common cold and flu season, is a high concern for people of all ages, and especially people with immunocompromised conditions. Finding solutions to improve the immune function includes integrating healthy lifestyle choices that build and maintain a healthy immune system. An all-natural supplement for motivating wellness, Bionox provides nitric oxide nutrition to help support the body’s defense against pathogens and infectious diseases and to keep the immune system balanced.

In 2005, Dr. Jay Wilkins, a naturopathic doctor and formulator of best- selling supplements, became interested in the astounding benefits of nitric oxide (NO) known as “the miracle molecule”. 1 Evidence shows that healthy levels of nitric oxide in the body supports cardiovascular health, healthy blood pressure, and widening blood vessels, as well as one of the most versatile players in the immune system. As people age, they produce less nitric oxide. For example, a person at age 40 may have up to 50% less NO than when at age 20.

Bionox formulated M3 Ultimate Nitric Oxide Nutrition with key ingredients that can boost and sustain NO throughout the body. There are two pathways for the conversion of nutrients into nitric oxide. The amino acids L-arginine and L-citrulline travel through the arginine-nitric oxide pathway. M3 contains the right amounts and ratio of arginine and citrulline for a 24-hour nitric oxide release. M3 adds nutrients of certain fruits and roots, such as pomegranate and beets, to generate NO through the nitrate/nitrite-nitric oxide pathway. Bionox includes nutrients from minerals, herbs, antioxidants, and vitamins that aid absorption, pH balance, and health benefits to increase optimum effectiveness of usage of NO in the body.

“I tell my patients that ‘keeping your shields up’ is key, “ shares Dr. Jay Wilkins. “Let’s do our part to shift your body into optimal health to give you the best opportunity to defend yourself and have vitality. “

There is a lot of research into understanding nitric oxide benefits for the immune system. For immune response, nitric oxide plays an important role in immunoregulation, as an intercellular messenger. Nitric oxide in the body has been shown to regulate immune response in the eradication of pathogens, inhibit pathogen replication, and activity of immune and inflammatory cells, as an important toxic defense molecule. 2 NO acts as a neurotransmitter, which are chemical messengers that transmit messages to the brain and the rest of the body. NO is important to keep the immune system strong through its ability to disable pathogens and its mobility.

In searching for natural products to boost the immune system, Bionox offers M3 as a one of the most up-to- date and comprehensive nitric oxide supplements. M3 should be taken twice daily, once in the morning and again in the evening, ensuring 24-hour nitric oxide benefits.

Bionox M3 is naturally sweetened with organic inulin, stevia, monk fruit, and natural flavors. M3 is vegetarian, gluten-free, soy-free, made in the USA, sugar- free and non-GMO.

M3 Ultimate Nitric Oxide Nutrition can be purchased in 30 or 60 scoop containers in Original Berry Flavor or Citrus Flavor. Individual packets are also available on bionoxusa.com/ or on amazon.com.

About BioNox

Bionox® was founded by Dr. Jay Wilkins, a naturopathic doctor who has been in the health and wellness industry for over 25 years. As a health practitioner, Dr. Jay Wilkins was interested in the science of nutrition and supplementation. When discovering the effectiveness of nitric oxide to maximize health in the body, Dr. Jay Wilkins researched and developed Bionox’s first product, as their flagship product - M3 Ultimate Nitric Oxide Nutrition. M3 provides a potent combination of nutrients that activates the innate power of the body to realize optimum health. Bionox mission is to motivate all to unlock their own wellness through providing trusted solutions to overcome life’s challenges and live life fully. Their potent formulas for nitric oxide nutrition, Bionox M3 comes in both Citrus Flavor and Original Berry Flavor, available as a one-month supply, 15-day supply, and stick packs. Bionox has developed other blends for motivating wellness with their Ultimate Sugar Balance Support, Chelanox, M-Mune3, and Nox3 Daily Greens. Bionox is motivating all to live life, fully.

Media Contact

For more information about Bionox please visit bionoxusa.com/. For media inquiries, requests for product samples, high-res images, or to set up an interview with Bionox founder Dr. Jay Wilkins, please contact Halle Barnett, [email protected] or at 678-756-8282.

1 Bezaitis, Athan. (2009, Feb). How Nitric Oxide Maintain Health. Retrieved from: https://news.usc.edu/14039/How-Nitric-Oxide- Maintains-Health/

2 Tripathi, Parul. (2007). Nitric oxide and immune response. Retrieved from https://pubmed.ncbi.nlm.nih.gov/18341206/