What Works Better To Boost Nitric Oxide, Arginine, Citrulline or Beets?

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Arginine, how it works to boost nitric oxide

Arginine is an amino acid found in many foods that we eat and boosts nitric oxide. When we consume arginine, our body uses it to produce a molecule called nitric oxide. Nitric oxide is important because it helps to relax the blood vessels in our body, which allows more blood to flow through them.

Think of your blood vessels like straws – if they are narrow, it’s harder for the liquid to flow through them. But if the straws are wider, the liquid can flow more easily. Nitric oxide helps to widen the blood vessels, which allows more blood to flow through them.

When we have more blood flowing through our blood vessels, it delivers more oxygen and nutrients to our muscles and organs. This is why athletes use arginine to improve their performance.

Arginine is an amino acid that our body uses to produce nitric oxide. Nitric oxide helps to widen our blood vessels, which allows more blood to flow through them and deliver oxygen and nutrients to our muscles and organs.

Nitric Oxide Booster

As we age

Your arteries can lose elasticity over time due to a process called arteriosclerosis. This happens when substances such as cholesterol and fat build-up. This occurs in the walls of the veins, forming a plaque. Over time, the plaque can harden and cause the walls of the arteries to become stiff and less flexible.

Arteriosclerosis is a gradual process with various factors, including a poor diet and lack of exercise. Smoking, high blood pressure, and high-stress levels can also cause it. These factors can damage the inner lining of the arteries. This causes inflammation and makes it easier for plaque to build up.

The Arteries

As the arteries become less elastic, it can become more difficult for blood to flow through them. This increases the risk of heart disease, stroke, and other health problems. That’s why it’s essential to maintain the health of your arteries by eating a healthy diet. Exercising regularly and not smoking also play an important role.

Why may arginine not work for some people?

Arginine may not work for some people because our bodies can have different levels of effectiveness in converting arginine to nitric oxide. Also, the optimal dose of arginine varies from person to person. Some individuals may not be taking enough to see a noticeable effect. If you have been taking a cheap, low-dose arginine and noticed no effects, that could be the case for you.


The beginning dose for effective arginine supplementation starts at 5000 mg for some.

What do most studies conclude about nitric oxide and arginine?

Most studies conclude that arginine can potentially increase nitric oxide levels in the body. This can improve blood flow, exercise performance, and cardiovascular health. However, the results of studies have been mixed, with some studies showing significant benefits and others showing no effect. Why is this?

What about the studies that show that arginine doesn’t boost nitric oxide?

Mouthwash, antibiotics, and antacids can hurt nitric oxide production in the body.

There are hundreds of published studies on arginine and its effects on human health. Studies include researching potential benefits for cardiovascular health, exercise performance, and erectile dysfunction, among other areas.

The results of these studies are mixed, with some showing a net positive result and others being inconclusive or negative.

Is It Good Science?

Regarding antacid use or mouthwash use in these studies, some take these factors into account, while many others do not. When these factors are not taken into account, it can potentially skew the results of the study. This is because of the absorption of the supplement and the conversion of nitrates to nitric oxide in the body. The use of certain chemicals can negatively influence the effectiveness of arginine.

For example, if people in a study are using antacids, it could reduce the acidity of the stomach and potentially reduce the absorption of arginine in the body. Thus making it more difficult to see the supplement’s effects. Similarly, if people in a study are using mouthwash, it could potentially reduce the production of nitric oxide from the nitrates in their diet. Again making it more difficult to see the effects of the arginine supplement.

Therefore, it is important for researchers to control for these factors and other potential confounding variables in their studies. Participants must be screened for usage to get an accurate picture of the effects of arginine supplementation on health. Many so-called studies showing that arginine is not useful are guilty of not properly controlling the intake of these substances by participants in the study.

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Nitric Oxide Boosters

Citrulline as a Nitric Oxide Booster

The kidneys convert citrulline into arginine, which the body then uses to produce nitric oxide. While citrulline does not directly convert into nitric oxide like arginine, it can increase arginine levels in the body more effectively than taking arginine supplements. This effectiveness comes from the liver breaking down much of the orally taken arginine before it reaches the bloodstream. In contrast, the liver does not break down citrulline as much, allowing it to raise arginine levels in the body more efficiently.

Time Released

The time frame for citrulline to boost nitric oxide levels in the body may be slightly longer than for arginine. This is because it takes time for the kidneys to convert citrulline into arginine. The effects of citrulline may last longer than arginine due to its slower absorption and longer half-life in the body.

Some studies have suggested that citrulline may be more effective than arginine at improving exercise performance, while others have suggested that arginine may be more effective for certain cardiovascular conditions.

Many studies have suggested that taking both supplements together may be more effective at increasing nitric oxide levels in the body.


One study that has shown promise for citrulline and human health is a 2017 study published in the Journal of the International Society of Sports Nutrition. The study found that citrulline supplementation was effective at improving exercise performance and reducing muscle soreness, with no reported adverse effects.

booster of no

Boost Nitric Oxide With Beetroot

Beetroot contains high levels of inorganic nitrate, which is converted in the body into nitric oxide. NO is a signaling molecule that helps to regulate blood flow, blood pressure, and vascular function. Nitric oxide works by relaxing the smooth muscle cells in the walls of blood vessels. Thus allowing them to dilate and improve blood flow. This, in turn, can help to reduce blood pressure, improve oxygen delivery to tissues, and support cardiovascular health.

Several studies have investigated the effects of beetroot supplementation on cardiovascular health. For example, a study of 22 randomized controlled trials found that beetroot juice consumption was associated with significantly reducing blood pressure. This was in healthy individuals and those with hypertension (Siervo et al., 2018). Another study found that beetroot juice improved endothelial function in patients with heart failure (Gheibi et al., 2019).

Beetroot For Exercise

In addition to its cardiovascular benefits, beetroot supplementation may also improve exercise performance. Several studies have reported that beetroot supplementation can increase time to exhaustion. They also show improved running and cycling performance in trained and untrained individuals (Jones et al., 2018). One mechanism for this effect may be the ability of nitric oxide to improve blood flow to the muscles. This then increases oxygen and nutrient delivery to the body.

Bodybuilders may also benefit from beetroot supplementation due to its potential to enhance muscle growth and recovery. A study by Cermak et al. (2012) found that beetroot juice supplementation increased muscle protein synthesis in healthy men following exercise.

Timeframe For Boosting Nitric Oxide

The effects of beetroot on nitric oxide production and cardiovascular function may last for several hours following consumption. The exact duration of the effect may vary depending on the individual and the dose. In contrast, the effects of arginine and citrulline on nitric oxide production may be more prolonged. This is because they are involved in synthesizing nitric oxide within the body.

Beetroot supplementation appears to be generally safe, with few reported adverse effects.

There is indeed much evidence to suggest that combining beetroot with arginine or citrulline is beneficial. The combo may enhance the effects on nitric oxide production and cardiovascular function. A study by Lidder et al. (2019) found that combining beetroot juice and citrulline supplementation improved blood flow and reduced blood pressure in healthy adults compared to either supplement alone.

There is indeed much evidence to suggest that combining beetroot with arginine or citrulline may enhance the effects on nitric oxide production and cardiovascular function